Wednesday, May 30, 2007

Getting from discovery to trial in adult stem cell treatments

Scientists are syaing that the current bottleneck is moving forward from basic scientific discovery to a basic clinical trial in time to help people with devastating diseases.
Patience may well be a virtue, but if you are living with and/or loving someone who is dying before your eyes you would be keen to get help right now. Such a story was published this week from Utah where nine-year old twins died of Batten Disease - a rare and fatal neurological disorder. There is research going on now in Oregon using adult stem cells that one day soon may be able to help sufferers but it's a case of 'too little, too late'.
Many patients with end-stage heart disease, cardiomyopathy or ischemic heart disease can attest to the fact that it was impossible for them to get onto a trial. They were excluded because of age, co-morbid factors, prognosis, etc etc and left without hope. Yes, we need clinical trials on humans and longitudinal studies as well. But if you are a no-option heart patient or PAD patient at this moment, you do not have the luxury of time.
This is why people are taking charge of their own health and seeking treatment that is safe and readily available. All the better if they can get adult stem cell therapy that has a track record of good patient outcomes as measured by self-report and clinical measures. One day published trial results will catch up with what is happening now.
It is a good thing that heart failure, cardiomyopathy and ischemic heart disease patients can trust those who have gone before them and know that they will receive excellent care and the excellent odds of an outcome better than they could possibly have hoped for. Further, they are going to be helped by their body's own repair kit - their adult stem cells derived from their own blood - so there are no rejection problems to cope with.

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